Office Politics: When to stand your ground and when to be diplomatic

Rather than posting another how-to article, I'd rather hear from you the reader about your questions regarding working in a multinational and the troubles or challenges you have encountered in your time there. This post our topic will be: Office Politics. Knowing how to navigate relationships, be strong, but not too strong when you encounter difficult individuals, or even knowing how to tolerate those little things that drive you nuts not only can help you advance in your career, but even provide opportunities in other organizations or avoid the ax when the time comes for your company to cut staff. What questions do you have or encounters you wish you knew how to handle before they got too crazy?